ATTR amyloidosis

ATTR amyloidosis is the term for a group of rare diseases that are caused by a protein – called transthyretin (TTR) – not acting in quite the way it should.

In ATTR amyloidosis, this TTR protein becomes unstable and breaks apart. There are a number of reasons for this happening but, when it does, pieces of the abnormal protein can clump together. This ends up creating deposits of amyloid.

If amyloid deposits build up in your tissues and/or organs this can create health problems. Common examples include problems with the heart, nerves and digestive system.

In this section you will find more information on the two key forms of ATTR amyloidosis, as well as certain factors that may increase your risk of the disease.

ATTR amyloidosis

ATTR amyloidosis is the term for a group of rare diseases that are caused by a protein – called transthyretin (TTR) – not acting in quite the way it should.

In ATTR amyloidosis, this TTR protein becomes unstable and breaks apart. There are a number of reasons for this happening but, when it does, pieces of the abnormal protein can clump together. This ends up creating deposits of amyloid.

If amyloid deposits build up in your tissues and/or organs this can create health problems. Common examples include problems with the heart, nerves and digestive system.

In this section you will find more information on the two key forms of ATTR amyloidosis, as well as certain factors that may increase your risk of the disease.